Research Category

Anti Aging Research

Extend Vitality. Protect Longevity.

TelomeresMitochondriaCell RenewalLongevitySenescence

Peptides researched for their telomere-supporting, mitochondrial-protective, and senolytic properties aligned with healthy longevity science.

6

Research Compounds

28

Scientific References

Monthly

Updated

Research Snapshot

Evidence Summary

Research Areas

TelomeresMitochondriaCell RenewalLongevitySenescence

Mechanisms

Telomerase ActivationCardiolipin ProtectionAMPK ActivationThymic Restoration

Research Status

SS-31 (Elamipretide) in Phase II clinical trials. Epitalon and Thymalin backed by Russian gerontology research spanning 35+ years.

Evidence Base

6

Compounds

28+

References

Research Overview

What this field
investigates

What we research

The Anti Aging category investigates peptides studied for their telomere-supporting, mitochondrial-protective, and senolytic properties — compounds at the intersection of geroscience and molecular biology.

How compounds are grouped

Compounds are grouped by longevity mechanism: telomerase activators (Epitalon), mitochondrial protectants (SS-31, MOTS-c), thymic restorers (Thymalin, Thymosin Alpha-1), and skin remodeling peptides (GHK-Cu). Each addresses a different hallmark of aging.

Research considerations

Anti-aging peptide research draws from Russian gerontology (Epitalon, Thymalin) and Western mitochondrial biology (SS-31, MOTS-c). Human longevity data is inherently long-term and limited. These compounds target biological aging processes, not cosmetic outcomes.

Research Category

All Compounds

6 total
Epitalon
Peptide

C14H22N4O9

Epitalon

The Telomere Peptide — Resets the Biological Clock

Epitalon (Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the natural polypeptide Epitha...

Telomerase activation and …Pineal gland melatonin reg…
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SS-31
Peptide

C26H41N7O6

SS-31

Szeto-Schiller Peptide — Mitochondrial Protector

SS-31 (Szeto-Schiller Peptide 31, also known as Elamipretide or MTP-131) is a tetrapeptide that selectively ta...

Mitochondrial inner membra…Cardiolipin protection and…
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Thymalin
Research

Thymalin

The Thymic Peptide for Immune Rejuvenation

Thymalin is a natural polypeptide complex isolated from calf thymus glands. Developed in Russia alongside Epit...

T-cell maturation and thym…Immune system rejuvenation…
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MOTS-c
Peptide

C92H152N26O26S

MOTS-c

The Mitochondrial-Encoded Peptide for Metabolic Youth

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a mitochondria-derived peptide (MDP) encod...

Insulin sensitivity and gl…Regulation of folate cycle…
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Humanin
Peptide

C97H168N34O29S

Humanin

The Cytoprotective Mitochondrial Peptide

Humanin is a 21-amino-acid mitochondria-derived peptide encoded within the 16S rRNA gene of the mitochondrial ...

Neuroprotection against be…Anti-apoptotic signaling i…
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FOXO4-DRI
Peptide

C168H258N44O49S

FOXO4-DRI

Senolytic Peptide — Selective Apoptosis of Senescent Cells

FOXO4-DRI is a synthetic D-retro-inverso peptide designed to disrupt the interaction between FOXO4 and p53 in ...

Selective elimination of s…Reversal of age-related fu…
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