Cognitive Research
Sharpen the Mind. Elevate Focus.
Peptides investigated for their nootropic and neuroprotective potential, supporting mental clarity, memory consolidation, and neurological resilience.
7
Research Compounds
38
Scientific References
Monthly
Updated
Research Snapshot
Evidence Summary
Research Areas
Mechanisms
Research Status
Clinical use in Russia (Semax, Selank, Cerebrolysin). Western research primarily preclinical. Dihexa in early-stage neuroscience research.
Evidence Base
7
Compounds
38+
References
Related Research
Research Overview
What this field
investigates
What we research
The Cognitive category explores peptides investigated for their nootropic and neuroprotective potential — compounds that modulate neurotransmitter systems, upregulate neurotrophic factors, and support synaptic plasticity.
How compounds are grouped
Compounds are grouped by their cognitive mechanism: BDNF-enhancing peptides (Semax, Noopept), synaptogenic compounds (Dihexa), neurotrophic blends (Cerebrolysin), and anxiolytic nootropics (Selank). Each targets different aspects of cognitive function.
Research considerations
Cognitive peptides have been studied primarily in Russian clinical contexts (Semax, Selank, Cerebrolysin) and Western preclinical models. Regulatory status varies by jurisdiction. These are research compounds, not dietary supplements or approved medications.
Research Category
All Compounds
C37H51N9O10S
Semax
ACTH Analogue — Neuro-Enhancement and Neuroprotection
Semax is a heptapeptide analogue of ACTH(4-10) developed in Russia and used clinically there for stroke, cogni...
C33H57N11O9
Selank
The Anxiolytic Nootropic Peptide
Selank is a synthetic heptapeptide analogue of the endogenous human peptide tuftsin, developed by the Institut...
Dihexa
The Synaptogenic Peptide — Next-Level Cognitive Enhancement
Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a potent cognitive enhancer developed at Washington Sta...
PE-22-28
The Novel Anti-Depressant Peptide
PE-22-28 is a synthetic truncated analogue of spadin, which is itself a fragment of the TREK-1 potassium chann...
C17H22N2O4
Noopept
The Dipeptide Nootropic
Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) is a synthetic dipeptide-derived compound with potent noo...
Cerebrolysin
The Neuropeptide Mixture for Brain Repair
Cerebrolysin is a peptide preparation derived from porcine brain tissue consisting of low-molecular-weight pep...
P21
CNTF-Derived Neurogenic Peptide
P21 is a synthetic peptide derived from Ciliary Neurotrophic Factor (CNTF), engineered to retain the neurotrop...
Knowledge Base
Research Articles
Educational guides and mechanism explanations relevant to cognitive research.
Semax: BDNF Upregulation and Cognitive Enhancement
A review of Semax's mechanism — from melanocortin receptor modulation to BDNF and NGF upregulation in the hippocampus.
Dihexa: Synaptogenesis and Spatial Memory
Washington State University research on Dihexa's dramatic effects on synaptogenesis and Morris water maze performance.
Noopept: The Dipeptide Nootropic
Understanding Noopept's prodrug conversion, BDNF/NGF upregulation, and its position as a dipeptide nootropic.
Still not sure?
Use our interactive Research Navigator to discover compounds commonly investigated for your specific research goals. Educational only — no products, no pricing.
Start Research NavigatorExplore More