BPC-157
The Body Protection Compound
Molecular Data
- Formula
- C62H98N16O22
- Molecular Weight
- 1419.56 g/mol
- Sequence
- Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu…
01
Overview
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a naturally occurring protein found in gastric juice. It has been extensively studied in preclinical models for its remarkable regenerative properties across a wide range of tissues including tendons, ligaments, muscle, nerve, and gut mucosa. Research suggests it may accelerate wound healing and modulate multiple growth factor pathways.
02
Mechanism of Action
BPC-157 is thought to interact with the nitric oxide (NO) system and upregulate the expression of growth factors such as VEGF, EGF, and FGF. It appears to modulate the FAK-paxillin pathway, promoting cell migration and wound closure. Additionally, research indicates interactions with the dopaminergic and serotonergic systems.
03
Research Highlights
Studies in rodent models demonstrate accelerated healing of Achilles tendon transection injuries
Gastric cytoprotection research shows protective effects against NSAID-induced gut damage
Neurological studies indicate potential neuroprotective and neuroregenerative properties
04
Dosage
Administration & Timing
Subcutaneous (SC) injection into abdominal or gluteal subcutaneous tissue, typically once or twice daily. Research protocols often administer on an empty stomach, morning and/or evening, independent of food timing.
Dosage Guidelines
Cycle Length
2–4 weeks, followed by an observation period of equal length before re-evaluation.
05
Reconstitution
Solvent
Bacteriostatic Water (0.9% benzyl alcohol)
Volume
2 mL added to a 5 mg vial
Concentration
2.5 mg/mL (2,500 mcg/mL)
Storage
Refrigerate at 2–8 °C; protect from light. Discard 30 days after reconstitution.
Notes
BPC-157 is stable in solution; gently swirl — do not shake. A 250 mcg dose equals 10 units on a U-100 syringe at this concentration.
Research Reference Only
Dosage and reconstitution values reflect commonly cited ranges from published research literature and are presented for educational and research reference only. This is not medical advice or a dosing recommendation. HEXAGEN does not endorse human use of any compound. Always consult a qualified healthcare professional.
Research Disclaimer
BPC-157 is for educational and research purposes only. Not intended as medical advice. Consult a qualified healthcare professional before making any health-related decisions.
Related Compounds
View All
BPC-157 Knowledge Graph
Explore how BPC-157 connects to mechanisms, research goals, related compounds, research stacks, and scientific references. Drag nodes, zoom, and filter by type.
No nodes match the active filters.
BPC-157 — Common Research Questions
What is BPC-157?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a naturally occurring protein found in gastric juice. It has been extensively studied in preclinical models for its ... BPC-157 belongs to the Healing research category and is studied for its the body protection compound.
How does BPC-157 work?
BPC-157 is thought to interact with the nitric oxide (NO) system and upregulate the expression of growth factors such as VEGF, EGF, and FGF. It appears to modulate the FAK-paxillin pathway, promoting cell migration and wound closure. Additionally, research indicates interactions with the dopaminergic and serotonergic systems.
What are the key research benefits of BPC-157?
Tendon and ligament repair acceleration. Gut lining protection and restoration. Muscle healing and anti-inflammatory effects. Nerve regeneration support. Angiogenesis promotion for improved blood flow. Cytoprotective effects on the GI tract.
What is the molecular structure of BPC-157?
BPC-157 has the molecular formula C62H98N16O22 and a molecular weight of 1419.56 g/mol. Its amino acid sequence is Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. This structural information is important for researchers studying receptor binding and pharmacokinetics.
What does the research say about BPC-157?
Studies in rodent models demonstrate accelerated healing of Achilles tendon transection injuries Gastric cytoprotection research shows protective effects against NSAID-induced gut damage Neurological studies indicate potential neuroprotective and neuroregenerative properties These findings are based on preclinical and clinical research. BPC-157 is a research compound and these studies do not constitute medical advice.
Is BPC-157 FDA approved?
No. BPC-157 is not FDA-approved for any indication. It is a research chemical studied in preclinical and early clinical research. These compounds are not approved for human therapeutic use and should only be studied in appropriate research settings.
What category does BPC-157 belong to?
BPC-157 belongs to the Healing category, which focuses on research-grade peptides studied for their regenerative and healing properties, supporting tissue repair, inflammation modulation, and systemic recovery. You can explore more compounds in this category on the Healing pillar page.
Related Articles
BPC-157: Mechanism of Action in Tendon Repair
Examining the FAK-paxillin pathway and growth factor upregulation that underlies BPC-157's regenerative effects in preclinical tendon injury models.
Thymosin Beta-4: From Actin Regulation to Cardiac Repair
How TB-500's interaction with G-actin promotes cell migration and its implications for cardiac tissue repair research.
GHK-Cu: Copper Peptides in Skin Remodeling
Exploring three decades of research on GHK-Cu's role in collagen synthesis, skin remodeling, and hair follicle stimulation.
Scientific References
Sikiric et al. — "Brain-gut and liver-gut axis in BPC 157″ (Curr Pharm Des, 2021)
Sikiric et al. — "Stable gastric pentadecapeptide BPC 157″ (J Physiol Pharmacol, 2018)
Centr. Europ. J Pharmacol — Tendon healing model in rats, 2011
Studies in rodent models demonstrate accelerated healing of Achilles tendon transection injuries
Gastric cytoprotection research shows protective effects against NSAID-induced gut damage
Neurological studies indicate potential neuroprotective and neuroregenerative properties