Pharmacology
Melanocortin Receptor
Melanocortin receptors are a family of G-protein-coupled receptors (MC1R-MC5R) that mediate pigmentation, sexual function, appetite, and inflammation.
Detailed Explanation
The melanocortin system includes five receptor subtypes. MC1R regulates melanogenesis (targeted by Melanotan I and II). MC3R and MC4R regulate sexual function and appetite (targeted by PT-141). MC5R affects exocrine glands. KPV interacts with MC1R and MC3R for anti-inflammatory effects. Understanding receptor selectivity is key to predicting peptide effects.