Peptide Science

Peptide Bond

A peptide bond is a covalent chemical bond formed between the carboxyl group of one amino acid and the amino group of another, releasing a molecule of water.

Detailed Explanation

Peptide bonds are amide linkages that form the backbone of peptides and proteins. They are planar and rigid due to partial double-bond character, which constrains the three-dimensional folding of the peptide chain. The directionality of peptide bonds (N-terminus to C-terminus) defines the primary structure of a peptide.