Pharmacology
SARM
Selective Androgen Receptor Modulators (SARMs) are compounds that activate the androgen receptor in muscle and bone while minimizing activity in reproductive tissues.
Detailed Explanation
SARMs achieve tissue selectivity through differential co-regulator recruitment compared to testosterone. They activate anabolic genes in muscle while acting as partial agonists in prostate tissue. Key SARMs include RAD-140 (Testolone), LGD-4033 (Ligandrol), Ostarine (MK-2866), Andarine (S-4), and S23. YK-11 is unique in combining SARM activity with myostatin inhibition.