Biology
Follistatin
Follistatin is a glycoprotein that binds and neutralizes myostatin and activin, removing the inhibitory brake on muscle growth.
Detailed Explanation
Follistatin-344 is a recombinant form studied for muscle wasting conditions. By binding myostatin (GDF-8) and activin with high affinity, it prevents their interaction with ActRII receptors, allowing unopposed myoblast fusion and fiber growth. Research models show 2-4x muscle mass increases with follistatin overexpression.