Endocrinology

Growth Hormone

Growth hormone (GH or HGH) is a peptide hormone produced by the pituitary gland that stimulates growth, cell reproduction, and regeneration.

Detailed Explanation

GH acts through the JAK2/STAT5b signaling pathway, with many effects mediated by IGF-1 produced in the liver. Several peptides stimulate GH release: GHRH analogues (CJC-1295, Tesamorelin, Sermorelin) act at GHRH receptors, while GHRPs (Ipamorelin, GHRP-2, GHRP-6, Hexarelin) act at the ghrelin receptor. MK-677 is an oral ghrelin receptor agonist. GH promotes lipolysis, lean mass, and metabolic regulation.

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